Tata BK, Mimouni NEH, Barbotin AL, Malone SA, Loyens A, Pigny P, Dewailly D, Catteau-Jonard S, Sundström-Poromaa I, Piltonen TT, Dal Bello F, Medana C, Prevot V, Classadonte J, Giacobini P (2018) Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood. Nature Medicine. 2018. DOI:10.1038/s41591-018-0035-5
Belle M, Godefroy D, Couly G, Malone SA, Collier F, Giacobini P, Chedotal A (2017) Tridimensional Visualization and Analysis of Early Human Development. Cell. DOI: http://dx.doi.org/10.1016/j.cell.2017.03.008
Casoni F, Malone SA, Belle M, Luzzati L, Collier F, Allet C, Hrabovszky E, Rasika S, Prevot V, Chédotal A, Giacobini P (2016) Development of the Neurons Controlling Fertility in Humans: New Insights from 3D Imaging and Transparent Fetal Brains. Development DOI: 10.1242/dev.139444
Cimino I., Casoni F., Liu X., Messina A., Parkash J., Jamin S.P., Catteau-Jonard S. Collier F., Baroncini M., Dewailly D., Pigny P., Prescott M, Campbell R., Herbison A.E., Prevot V., Giacobini P. (2016) Novel Role for Anti-Müllerian Hormone in the Regulation of GnRH Neuron Excitability and Hormone Secretion. Nature Communications DOI: 10.1038/ncomms10055.
Boehm U., Bouloux P.M., Dattani M.T., de Roux N., Dodé C., Dunkel L., Dwyer A.A., Giacobini P., Hardelin JP., Juul A., Maghnie M., Pitteloud N., Prevot V., Raivio T., Tena-Sempere M., Quinton R. and Young J. (2015). European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment. Nature Reviews Endocrinology (doi:10.1038/nrendo.2015.112). Review article.
Parkash J., Messina A., Langlet F., Cimino I., Loyens A., Mazur D., Gallet S., Balland E., Malone S.A., Pralong F., Cagnoni G., Schellino R., De Marchis S., Mazzone M., Pasterkamp R.J., Tamagnone L., Prevot V., Giacobini P. (2015). Semaphorin7A regulates neuroglial plasticity at the adult hypothalamic median eminence. Nature Communications. DOI:10.1038/ncomms7385.
Giacobini P., Parkash J., Campagne C., Messina A., Casoni F., Vanacker C., Langlet F., Hobo B., Cagnoni G., Gallet S., Hanchate N.K., Mazur D., Taniguchi M., Mazzone M., Verhaagen J., Ciofi P., Bouret S.G., Tamagnone L., Prevot V. (2014). Brain Endothelial Cells Control Fertility through Ovarian- Steroid–Dependent Release of Semaphorin 3A. PLoS Biology DOI: 10.1371/journal.pbio.1001808. Weekly Editors’ pick. BPoD – Biomedical Picture of the Day (MRC Clinical Science Center, UK)
Parkash J., Cimino C., Ferraris N., Casoni F., Wray S., Cappy H, Prevot V., Giacobini P. (2012). Suppression of β1-Integrin in Gonadotropin-Releasing Hormone (GnRH) Cells Disrupts Migration and Axonal Extension Resulting in Severe Reproductive Alterations. The Journal of Neuroscience 32(47):16992–17002.
Hanchate N. K. *, Giacobini P. *, Lhuillier P., Parkash J., Espy C., Fouveaut C., Leroy C., Baron S., Campagne C., Vanacker C., Collier F., Cruaud C., Meyer V., García-Piñero A., Dewailly D., Cortet-Rudelli C., Gersak K., Metz C., Chabrier G., Pugeat M., Young J., Hardelin J.P., Prevot V., Dodé C (2012). SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome. PLoS Genetics 8(8): e1002896. * Equal contribution
Messina A., Ferraris N., Wray S., Cagnoni G., Donohue D.E., Casoni F., Kramer P.R., Derijck A.A.H., Adolfs Y., Fasolo A., Pasterkamp R.J., Giacobini P.* (2011) Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility in mice. Human Molecular Genetics 20(24):4759-74.
Giacobini P., Messina A., Morello F., Ferraris N., Corso S., Penachioni J., Giordano S., Tamagnone L., Fasolo A. (2008). Semaphorin 4D regulates gonadotropin hormone–releasing hormone-1 neuronal migration through PlexinB1–Met complex. The Journal of Cell Biology 183 (3): 555-566.
Awarded an ERC-Consolidator Grant: « Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions ».
Federation pour la recherche sur le cerveau (FRC), “Espoir en tête” 2016, France. Title: Optical clearing and light-sheet laser-scanning ultramicroscopy: a powerful tool to study brain connectivity in physiological and pathological conditions.
ANR (French National Research Agency): RoSes and GnRH, Role: PI-Coordinator. Title: The role of semaphorin-signalling in the neuroendocrine control of reproduction. 2014-2017.
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