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Original Research Papers
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Review Papers
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Book Chapters

2022

Original Research Articles

  1. Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions.
    Imbernon M, Saponaro C, Helms HCC, Duquenne M, Fernandois D, Deligia E, Denis RGP, Chao DHM, Rasika S, Staels B, Pattou F, Pfrieger FW, Brodin B, Luquet S, Bonner C, Prevot V.  Cell Metab. 2022 Jul 5;34(7):1054-1063.e7. doi: 10.1016/j.cmet.2022.06.002. Epub 2022 Jun 17. PMID: 35716660
  2. Neonatal leptin antagonism improves metabolic programming of postnatally overnourished mice. Colldén G, Caron E, Bouret SG. Int J Obes (Lond). 2022 Jun;46(6):1138-1144. doi: 10.1038/s41366-022-01093-4. Epub 2022 Feb 16. PMID: 35173277

  3. Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels.
    Cecon E, Fernandois D, Renault N, Coelho CFF, Wenzel J, Bedart C, Izabelle C, Gallet S, Le Poder S, Klonjkowski B, Schwaninger M, Prevot V, Dam J, Jockers R. Cell Mol Life Sci. 2022 Jun 13;79(7):361. doi: 10.1007/s00018-022-04390-3.

Review Articles

  1. Sowing SARS-CoV-2 to reap neurodegeneration: A hamster study.
    Rasika S, Fernandois D, Prévot V. EBioMedicine. 2022 Jun;80:104071. doi: 10.1016/j.ebiom.2022.104071. Epub 2022 May 25. PMID: 35633617
  2. The polygamous GnRH neuron: Astrocytic and tanycytic communication with a neuroendocrine neuronal population.
    Prevot V, Sharif A. J Neuroendocrinol. 2022 May;34(5):e13104. doi: 10.1111/jne.13104. Epub 2022 Mar 1. PMID: 35233849
  3. Glycemic control: Tanycytes march to the beat of the suprachiasmatic drummer.
    Imbernon M, Dehouck B, Prevot V. Curr Biol. 2022 Feb 28;32(4):R173-R176. doi: 10.1016/j.cub.2022.01.038. PMID: 35231413
  4. Glial control of neuronal function.
    Prevot V. Nat Rev Endocrinol. 2022 Apr;18(4):195. doi: 10.1038/s41574-022-00640-3. PMID: 35115720
  5. Developmental programming of hypothalamic melanocortin circuits.
    Bouret SG. Exp Mol Med. 2022 Apr;54(4):403-413. doi: 10.1038/s12276-021-00625-8. Epub 2022 Apr 26. PMID: 35474338
  6. Molecular control of the development of hypothalamic neurons involved in metabolic regulation.
    Croizier S, Bouret SG. J Chem Neuroanat. 2022 Sep;123:102117. doi: 10.1016/j.jchemneu.2022.102117. Epub 2022 Jun 6. PMID: 35680104

2021

Original Research Articles

  1. GnRH neurons recruit astrocytes in infancy to facilitate network integration and sexual maturation.
    Pellegrino G, Martin M, Allet C, Lhomme T, Geller S, Franssen D, Mansuy V, Manfredi-Lozano M, Coutteau-Robles A, Delli V, Rasika S, Mazur D, Loyens A, Tena-Sempere M, Siepmann J, Pralong FP, Ciofi P, Corfas G, Parent AS, Ojeda SR, Sharif A, Prevot V. Nat Neurosci. 2021 Dec;24(12):1660-1672. doi: 10.1038/s41593-021-00960-z. Epub 2021 Nov 18. PMID: 34795451
  2. Defective autophagy in Sf1 neurons perturbs the metabolic response to fasting and causes mitochondrial dysfunction.
    Coupé B, Leloup C, Asiedu K, Maillard J, Pénicaud L, Horvath TL, Bouret SG. Mol Metab. 2021 May;47:101186. doi: 10.1016/j.molmet.2021.101186. Epub 2021 Feb 8. PMID: 33571700
  3. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
    Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. Nat Neurosci. 2021 Nov;24(11):1522-1533. doi: 10.1038/s41593-021-00926-1. Epub 2021 Oct 21. PMID: 34675436
  4. Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function.
    Duquenne M, Folgueira C, Bourouh C, Millet M, Silva A, Clasadonte J, Imbernon M, Fernandois D, Martinez-Corral I, Kusumakshi S, Caron E, Rasika S, Deliglia E, Jouy N, Oishi A, Mazzone M, Trinquet E, Tavernier J, Kim YB, Ory S, Jockers, R., Schwaninger, M., Boehm, U., Nogueiras, R., Annicotte, J.S., Gasman, S., Dam, J. & Prevot, V.
    Nat Metab 2021. 3: 1071-1090
  5. Tanycytic networks mediate energy balance by feeding lactate to glucose-insensitive POMC neurons.
    Lhomme T, Clasadonte J, Imbernon M, Fernandois D, Sauve F, Caron E, Lima N, Heras V, Martinez-Corral I, Muller-Fielitz H, Rasika S, Schwaninger M, Nogueiras R, Prevot V.
    J Clin Invest 2021. 131:e140521.10.1172/JCI140521
  6. Loss-of-function variants in SEMA3F and PLXNA3 encoding semaphorin-3F and its receptor plexin-A3 respectively cause idiopathic hypogonadotropic hypogonadism. Kotan, L.D., Ternier, G., Cakir, A.D., Emeksiz, H.C., Turan, I., Delpouve, G., Kardelen, A.D., Ozcabi, B., Isik, E., Mengen, E., Cakir, E.D.P., Yuksel, A., Agladioglu, S.Y., Dilek, S.O., Evliyaoglu, O., Darendeliler, F., Gurbuz, F., Akkus, G., Yuksel, B., Giacobini, P. & Topaloglu, A.K. (2021) Loss-of-Function Genetics in Medicine in press. Genet Med 2021. 23:1008-1016. doi: 10.1038/s41436-020-01087-5
  7. Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process. Mimouni NEH, Paiva I, Barbotin AL, Timzoura FE, Plassard D, Le Gras S, Ternier G, Pigny P, Catteau-Jonard S, Simon V, Prevot V, Boutillier AL, Giacobini P (2021) Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process. Cell Metab 33:513-530.e8.  DOI: 10.1016/j.cmet.2021.01.004

Review Articles

  1. Nutritional and developmental programming effects of insulin.
    Dearden L, Bouret SG, Ozanne SE. J Neuroendocrinol. 2021 Jan 13;33(4):e12933. doi: 10.1111/jne.12933. Online ahead of print. PMID: 33438814
  2. Neurogenesis in the adult hypothalamus: A distinct form of structural plasticity involved in metabolic and circadian regulation, with potential relevance for human pathophysiology Sharif A, Fitzsimons CP, Lucassen PJ. Handb Clin Neurol. 2021;179:125-140.
  3. Tanycytes in the infundibular nucleus and median eminence and their role in the blood-brain barrier.
    Prevot, V., Nogueiras, R. & Schwaninger, M. Handb Clin Neurol 2021, 180: 253-273.
  4. The KiNG of reproduction: Kisspeptin/ nNOS interactions shaping hypothalamic GnRH release. Delli, V., Silva, M.S.B., Prevot, V. & Chachlaki, K. Mol Cell Endocrinol 2021, 532:111302.
  5. New insights into anti-Mullerian hormone role in the hypothalamic-pituitary-gonadal axis and neuroendocrine development. Silva, M.S.B. & Giacobini, P. Cell Mol Life Sci 2021, 78: 1-16.
  6. A roadmap for the Human Developmental Cell Atlas. Haniffa, M., Taylor, D., Linnarsson, S., Aronow, B.J., Bader, G.D., Barker, R.A., Camara, P.G., Camp, J.G., Chedotal, A., Copp, A., Etchevers, H.C., Giacobini, P., Gottgens, B., Guo, G., Hupalowska, A., James, K.R., Kirby, E., Kriegstein, A., Lundeberg, J., Marioni, J.C., Meyer, K.B., Niakan, K.K., Nilsson, M., Olabi, B., Pe’er, D., Regev, A., Rood, J., Rozenblatt-Rosen, O., Satija, R., Teichmann, S.A., Treutlein, B., Vento-Tormo, R., Webb, S. & Human Cell Atlas Developmental Biological. Nature 2021. 597: 196-205.
  7. New insights into anti-Müllerian hormone role in the hypothalamic-pituitary-gonadal axis and neuroendocrine development. Silva MSB, Giacobini P.  Cell Mol Life Sci. 2021, 78:1-16. doi: 10.1007/s00018-020-03576-x.

Book Chapters

  1. Unveiling the Importance of Tanycytes in the Control of the Dialogue Between the Brain and the Periphery. Nampoothiri S, Duquenne M, Prevot V. 

    In: Tasker JG, et al., ed. Glial-Neuronal Signaling in Neuroendocrine Systems. Masterclass in Neuroendocrinology Series. Switzerland: Springer Nature:255-284, 2021.

2020

Original Research Articles

  1. The proportion of cleaved anti-Müllerian hormone is higher in serum but not follicular fluid of obese women independently of polycystic ovary syndrome. Peigné M., Pigny1 P., Pankhurst M.W., Drumez E., Loyens A., Dewailly D., Catteau-Jonard S., Giacobini P. Reproductive BioMedicine Online 2020 , 41:1112-1121. DOI: 10.1016/j.rbmo.2020.07.020.

  2. Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism. Messina A, Pulli K, Santini S, Acierno J, Känsäkoski J, Cassatella D, Xu C, Casoni F, Malone SA, Ternier G, Conte D, Sidis Y, Tommiska J, Vaaralahti K, Dwyer A, Gothilf Y, Merlo GR, Santoni F, Niederländer NJ, Giacobini P*, Raivio T*, Pitteloud N* Am J Hum Genet. 2020, 106:58-70. DOI:10.1016/j.ajhg.2019.12.003. * Equal contribution.
  3. Neuropilin-1 expression in GnRH neurons regulates prepubertal weight gain and sexual attraction. Vanacker C, Trova S, Shruti S, Casoni F, Messina A, Croizier S, Malone S, Ternier G, Hanchate NK, Bouret SG, Ciofi P, Giacobini P, Prevot V Embo J 2020. 39, e104633
  4. The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates. Park S, Aintablian A, Coupe B, Bouret SG Nat Commun 2020. 11, 1914

  5. Maternal obesity-induced endoplasmic reticulum stress causes metabolic alterations and abnormal hypothalamic development in the offspring. Park S, Jang A, Bouret SG PLoS Biol 2020. 18, e3000296

  6. Hypothalamic Structural and Functional Imbalances in Anorexia Nervosa. Florent V, Baroncini M, Jissendi-Tchofo P, Lopes R, Vanhoutte M, Rasika S, Pruvo JP, Vignau J, Verdun S, Johansen JE, Pigeyre M, Bouret SG, Nilsson IAK, Prevot V. Neuroendocrinology. 2020. 110, 552-562.

Review Articles

  1. Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome. Stener-Victorin E, Padmanabhan V, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA, Abbott DH. Endocr Rev. 2020. 41, 538-76.

  2. Nitric oxide signalling in the brain and its control of bodily functions. Chachlaki K, Prevot V. Br J Pharmacol. 2020,177:5437-5458. doi: 10.1111/bph.14800.

2019

Original Research Articles

  1. Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance. Van der Klaauw AA, Croizier S, Mendes de Oliveira E, Stadler LKJ, Park S, Kong Y, Banton MC, Tandon P, Hendricks AE, Keogh JM, Riley SE, Papadia S, Henning E, Bounds R, Bochukova EG, Mistry V, O’Rahilly S, Simerly RB, Consortium UK, , Minchin, J.E.N., Barroso, I., Jones, E.Y., Bouret, S.G. & Farooqi, I.S. Cell 2019. 176: 729-742 e18

  2. Non-nutritive Sweeteners Induce Hypothalamic ER Stress Causing Abnormal Axon Outgrowth. Park, S., Sethi, S. & Bouret, S.G. Front Endocrinol (Lausanne) 2019. 10, 876.

  3. Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism. Malone, S.A., Papadakis, G.E., Messina, A., Mimouni, N.E.H., Trova, S., Imbernon, M., Allet, C., Cimino, I., Acierno, J., Cassatella, D., Xu, C., Quinton, R., Szinnai, G., Pigny, P., Alonso-Cotchico, L., Masgrau, L., Marechal, J.D., Prevot, V., Pitteloud, N. & Giacobini, P. Elife 2019. 8: e47198.

  4. Defective AMH signaling disrupts GnRH neuron development and function and contributes  to hypogonadotropic hypogonadism. Malone SA, Papadakis GE, Messina A, Mimouni NEH, Trova S, Imbernon M, Allet C, Cimino I,  Acierno J, Cassatella D, Xu C, Quinton R, Szinnai G, Pigny P, Alonso-Cotchico L, Masgrau L,  Maréchal JD, Prevot V, Pitteloud N, Giacobini P. Elife. 2019. 8:e47198. doi: 10.7554/eLife.47198

  5. Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.  van der Klaauw AACroizier SMendes de Oliveira EStadler LKJPark SKong YBanton   MCTandon PHendricks AEKeogh JMRiley SEPapadia SHenning EBounds RBochukova   EGMistry VO’Rahilly SSimerly RBINTERVALUK10K ConsortiumMinchin JENBarroso IJones   EYBouret SGFarooqi IS. 2019.  176:729-742.e18. doi: 10.1016/j.cell.2018.12.009  

Review Articles

  1. Emerging Roles of Anti-Müllerian Hormone in Hypothalamic-Pituitary Function. Barbotin AL, Peigné M, Malone SA, Giacobini P. Neuroendocrinology. 2019. 109,218-229.

  2. Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism. García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH. Nat Neurosci. 2019. 22,7-14.

  3. Emerging Roles of Anti-Müllerian Hormone in Hypothalamic-Pituitary Function. Barbotin ALPeigné MMalone SAGiacobini P 2019. doi: 10.1159/000500689.

  4. Don’t Trust Your Gut: When Gut Microbiota Disrupt Fertility. Silva MSBGiacobini P. 2019, 30:616-618. doi: 10.1016/j.cmet.2019.09.005.

  5. New Developments in Reproductive and Stress Neuroendocrinology. Prevot VMillar RP. 2019, 109:191-192. doi: 10.1159/000502420. 

2018

Original Research Articles

  1. Central Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis. Croizier, S., Park, S., Maillard, J. & Bouret, S.G. Elife 2018. 7: e40429

  2. Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood Tata B, Mimouni NEH, Barbotin AL, Malone SA, Loyens A, Pigny P, Dewailly D, Catteau-Jonard S, Sundström-Poromaa I, Piltonen TT, Dal Bello F, Medana C, Prevot V, Clasadonte J, Giacobini P. Nat Med. 2018. doi: 10.1038/s41591-018-0035-5.

  3. A comparative study of the neural stem cell niche in the adult hypothalamus of human, mouse, rat and grey mouse lemur (Microcebus murinus) Pellegrino G, Trubert C, Terrien J, Pifferi F, Leroy D, Loyens A, Migaud M, Baronicini M, Maurage CA, Fontaine C, Prevot V, Sharif A J Comp Neurol. 2018. 526(9):1419-1443

  4. Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood Tata BK, Mimouni NEH, Barbotin AL, Malone SA, Loyens A, Pigny P, Dewailly D, Catteau-Jonard S, Sundström-Poromaa I, Piltonen TT, Dal Bello F, Medana C, Prevot V, Classadonte J, Giacobini P Nature Medicine. 2018. doi:10.1038/s41591-018-0035-5

  5. A comparative study of the neural stem cell niche in the adult hypothalamus of human, mouse, rat and grey mouse lemur (Microcebus murinus) Pellegrino G, Trubert C, Terrien J, Pifferi F, Leroy D, Loyens A, Migaud M, Baronicini M, Maurage CA, Fontaine C, Prevot V, Sharif A J Comp Neurol. 2018. doi: 10.1002/cne.24376

  6. Central Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis. Croizier SPark SMaillard JBouret SG. Elife. 2018. doi: 10.7554/eLife.40429.

Review Articles

  1. Wired for eating: how is an active feeding circuitry established in the postnatal brain Muscatelli F, Bouret SG. Curr Opin Neurobiol. 2018. 52, 165-171.

  2. Sex and gender differences in developmental programming of metabolism. Dearden L, Bouret SG, Ozanne SE. Mol Metab. 2018.15, 8-19.

  3. The special relationship: glia-neuron interactions in the neuroendocrine hypothalamus Clasadonte J & Prevot V Nature Reviews Endocrinology. 2018, 14:25-44.

  4. The versatile tanycyte: a hypothalamic integrator of reproduction and energy metabolism Prevot, V., B. Dehouck, A. Sharif, P. Ciofi, P. Giacobini, and J. Clasadonte. Endocrine Reviews. 2018. doi: 10.1210/er.2017-00235.

  5. The versatile tanycyte: a hypothalamic integrator of reproduction and energy metabolism Prevot V, Dehouck B, Sharif A, Ciofi P, Giacobini P, Clasadonte J Endocrine Reviews. 2018. 1;39(3):333-368. doi: 10.1210/er.2017-00235

  6. The special relationship: glia-neuron interactions in the neuroendocrine hypothalamus Clasadonte J & Prevot V Nature Reviews Endocrinology. 2018, doi:10.1038/nrendo.2017.124

Book Chapters

  1. Unveiling the Importance of Glia and Vascular Endothelial Cells in the Control of GnRH Neuronal Function Prevot V & Sharif A Herbison AE & Plant TM. The GnRH neuron and its Control. Wiley. Chapter 10, pp 225. doi 10.1002/9781119233275.ch10

General Audience

  1. Rôle des réseaux astrocytaires métaboliques dans le maintien de l’éveil Clasadonte J Med Sci (Paris) 2017; 34(3):199-202

2017

Original Research Articles

  1. Connexin 43-Mediated Astroglial Metabolic Networks Contribute to the Regulation of the Sleep-Wake Cycle Clasadonte, J., E. Scemes, Z. Wang, D. Boison, and P.G. Haydon. Neuron. 2017. 95:1365-1380.e5.

  2. Phenotyping of nNOS Neurons in the Postnatal and Adult Female Mouse Hypothalamus Chachlaki K, Malone SA, Qualls-Creekmore, Hrabovszky E, Munzberg H, Giacobini P, Ango F, Prevot V J Comp Neurol, 2017. 525:3177-3189

  3. Tridimensional Visualization and Analysis of Early Human Development Belle M, Godefroy D, Couly G, Malone SA, Collier F, Giacobini P, Chedotal A Cell. 2017. 169:161-173 e112

  4. Phenotyping of nNOS Neurons in the Postnatal and Adult Female Mouse Hypothalamus Chachlaki K, Malone SA, Qualls-Creekmore, Hrabovszky E, Munzberg H, Giacobini P, Ango F, Prevot V J Comp Neurol. 2017. 10.1002/cne.24257

  5. Tridimensional Visualization and Analysis of Early Human Development Belle M, Godefroy D, Couly G, Malone SA, Collier F, Giacobini P, Chedotal A Cell. 2017 DOI: http://dx.doi.org/10.1016/j.cell.2017.03.008

Review Articles

  1. The gentle art of saying NO: how nitric oxide gets things done in the hypothalamus Chachlaki K, Garthwaite J, Prevot V Nature Reviews Endocrinology. 2017, 13:521-535.

  2. When size matters: how astrocytic processes shape metabolism Sharif A, Prevot V Cell Metabolism. 2017, 25:995-996.

  3. The gentle art of saying NO: how nitric oxide gets things done in the hypothalamus Chachlaki K, Garthwaite J, Prevot V Nature Reviews Endocrinology. 2017, doi:10.1038/nrendo.2017.69

  4. Connecting metabolism and gonadal function: Novel central neuropeptide pathways involved in the metabolic control of puberty and fertility Manfredi-Lozano M, Roa J, Tena-Sempere M Frontiers in Neuroendocrinology. 2017, doi: 10.1016/j.yfrne.2017.07.008

  5. When size matters: how astrocytic processes shape metabolism Sharif A, Prevot V Cell Metabolism. 2017, doi:10.1016/j.cmet.2017.04.016

General Audience

  1. Les micro-ARN Nouveaux acteurs du contrôle hypothalamique de la fertilité Messina A, Langlet F, Prevot V Med Sci (Paris) 2017; 33:506-511

  2. Tanycytes hypothalamiques, barrière hématoencéphalique et rôle dans la régulation de l’homéostasie énergétique Florent V, Baroncini M, Prevot V Cahiers de Nutrition et de Diététique, 52)1):26-32

  3. Développement des neurones à GnRH dans le cerveau d’embryons humains Barbotin AL, Prevot V, Giacobini P Medi Sci (Pari) 2017; 33:376-379

2016

Original Research Articles

  1. Development of the neurons controlling fertility in humans: new insights from 3D imaging and transparent fetal brains Casoni FMalone SABelle M, Luzzati F, Collier F, Allet CHrabovszky ERasika SPrevot VChédotal VGiacobini P

  2. Loss of Magel2 impairs the development of hypothalamic Anorexigenic circuits Maillard J, Park S, Croizier S, Vanacker C, Cook JH, Prevot V, Tauber M, and Bouret Hum Mol Genet. 25:3208-3215, 2016

  3. A microRNA switch regulates the rise in hypothalamic GnRH production before puberty Messina A, Langlet F, Chachlaki K, Roa J, Rasika S, Jouy N, Gallet S, Gaytan F, Parkash J, Tena-Sempere M, Giacobini P, Prevot V Nat Neurosci. 2016 19, 835-844 doi:10.1038/nn.4298

  4. Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion Cimino I, Casoni F, Liu X, Messina A, Parkash J, Soazik P, Catteau-Jonard S, Collier F, Baroncini M, Dewailly D, Pigny P, Prescott M, Campbell R, Herbison A, Prevot V, Giacobini P Nat Commun. 2016, 7:10055

Review Articles

  1. Hypothalamic microRNAs flip the switch for fertility Messina A, Prevot V Oncotarget. 2016, DOI: 10.18632/oncotarget.14646

  2. Reproduction: A kiss to set the rhythm Shruti S, Prevot V elife. 2016, doi:e19823

  3. Programming the Brain from the Womb: Maternal Obesity Perturbs the Hypothalamic Blood-Brain Barrier Duquenne, M., Dehouck, B. & Prevot, V Endocrinology, 157:2201-2203, 2016

  4. Coexpression profiles reveal hidden gene networks Chachlaki & Prevot PNAS (doi: 10.1073/pnas.1600717113)

Book Chapters

  1. Ontogeny of Neuroendocrine Feeding Circuits Croizier S & Bouret SG Dickson SL, Mercer JG (eds) Neuroendocrinology of Appetite. Wiley & Sons Ltd, c3

General Audience

  1. Control of fertility: New player identified Anti-Mullerian hormone: an ovarian hormone exerting hypothalamic feedback? Catteau-Jonard S, Dewailly D, Prevot V, Cimino I & Giacobini P Med Sci (Paris), 32:441-444, 2016 Maternal obesity alters social brain programming by altering gut microbiota in progeny Barbotin AL, Giacobini P, Prévot V Med Sci (Paris). 32930-932, 2016

2015

Original Research Articles

  1. Semaphorin7A regulates neuroglial plasticity at the adult hypothalamic median eminence Parkash J, Messina A, Langlet F, Cimino I, Loyens A, Mazur D, Gallet S, Balland E, Malone SA, Pralong FP, Cagnoni, Schellino RDe Marchis, Mazzone MPasterkamp JRTamagnone L, Prevot V, Giacobini P Nat Commun. 2015, 6:6385 doi:10.1038/ncomms7385.
  2. Neonatal overnutrition causes early alterations in the central response to peripheral ghrelin Collden G, Balland E, Parkash J, Caron E, Langlet F, Prevot V, and Bouret SG. Mol Metab. 2015, 4(1):15-24.
  3. Neonatal ghrelin programs development of hypothalamic feeding circuits Steculorum SM, Collden G, Coupe B, Croizier S, Lockie S, Andrews ZB, Jarosch F, Klussmann S, and Bouret SG. J Clin Invest. 2015, 125(2):846-58.

Review Articles

Book Chapters

  1. Puberty in mice and rats Prevot V Plant, T.M., Zeleznik, J. (eds) Knobil and Neill’s Physiology of Reproduction. Elsevier, New York, pp 1395-1439, 2015
  2. Endothelial cell plasticity in the normal and injured central nervous system Vanacker C, Sharif A, Prevot P Chapter 4, CRC Press, 2015

2014

Original Research Articles

  1. Leptin dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction Bellefontaine N, Chachlaki K, Parkash J, Vanaker C, Colledge W, d’Anglemont de Tassigny X, Garthwaite J, Bouret SG, Prevot V. J Clin Invest 124:2550-2559, 2014.

  2. Brain Endothelial Cells Control Fertility through Ovarian-Steroid_dependent Release of Semaphorin 3A Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, Langlet F, Hobo B, Cagnoni G, Gallet S, Hanchate NK, Mazur D, Taniguchi M, Mazzone M, Verhaagen J, Ciofi P, Bouret SG, Tamagnone L, Prevot V. PLoS Biology 12(3):e1001808, 2014.

  3. Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain Balland E, Dam J, Langlet F, Caron E, Steculorum S, Falluel-Morel A, Anouar Y, Dehouck B, Trinquet E, Jockers R, Bouret SG, Prevot V. Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain. Cell Metab 19, 293-301, 2014. (also Cell Metab Previews p. 173-175)

Review Articles

  1. Tanycytes: a gateway to the metabolic hypothalamus Langlet, F J Neuroendocrinol 26, 753-760, 2014

Book Chapters

  1. Neurogenesis and gliogenesis in the postnatal hypothalamus: a new level of plasticity for the regulation of hypothalamic function Sharif A, Ojeda SR, Prevot V Junier MP, Kernie SG eds. Endogenous Stem Cell-Based Brain Remodeling in Mammals, Stem Cell Biology and Regenerative Medicine. New York: Springer Science+Business Media, Chapter 6, pp 105-136, 2014

2013

Original Research Articles

  1. Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain Langlet F, Muller A, Bouret SG, Prevot V, Dehouck B. J Comp Neurol. 2013521(15):3389-405 doi: 10.1002/cne.23355

  2. Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting Langlet F, Levin BE, Luquet S, Mazzone M, Messina A, Dunn-Meynell AA, Balland E, Lacombe A, Mazur D, Carmeliet P, Bouret SG, Prevot V, Dehouck B
. Cell Metab. 2013 Apr 2;17(4):607-17. doi: 10.1016/j.cmet.2013.03.004..

  3. Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons Schaeffer M, Langlet F, Lafont C, Molino F, Hodson DJ, Roux T, Lamarque L, Verdié P, Bourrier E, Dehouck B, Banères JL, Martinez J, Méry PF, Marie J, Trinquet E, Fehrentz JA, Prévot V, Mollard P. 
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1512-7. doi:10.1073/pnas.1212137110.

Review Articles

  1. Semaphorin signaling in the development and function of the gonadotropin hormone-releasing hormone system Messina A and Giacobini P Front. Endocrinol., 23 September 2013doi: 10.3389/fendo.2013.00133, 2013

  2. Flipping the tanycyte switch: how circulating signals gain direct access to the metabolic brain Prevot V, Langlet F, Dehouck B Aging 5:332-334, 2013

  3. Semaphorins in the development, homeostasis and disease of hormone systems Giacobini P, Prevot V Semin Cell Dev Biol 24:190-198, 2013

  4. Role of glia in the regulation of gonadotropin-releasing hormone neuronal activity and secretion Sharif A, Baroncini M, Prevot V Neuroendocrinology 98:1-15, 2013

  5. Organizational actions of metabolic hormones Bouret, S.G Front Neuroendocrinol 34, 18-26, 2013

2012

Original Research Articles

  1. Suppression of β1-integrin in gonadotropin-releasing hormone cells disrupts migration and axonal extension resulting in severe reproductive alterations. Parkash J, Cimino I, Ferraris N, Casoni F, Wray S, Cappy H, Prevot V, Giacobini P. J Neurosci. 2012 Nov 21;32(47):16992-7002. doi: 10.1523/JNEUROSCI.3057-12.2012.

  2. RIPping off GABA release in hypothalamic circuits causes obesity. Bouret SG. Cell Metab. 2012 Nov 7;16(5):557-8. doi: 10.1016/j.cmet.2012.10.014.

  3. SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome. Hanchate NK, Giacobini P, Lhuillier P, Parkash J, Espy C, Fouveaut C, Leroy C, Baron S, Campagne C, Vanacker C, Collier F, Cruaud C, Meyer V, García-Piñero A, Dewailly D, Cortet-Rudelli C, Gersak K, Metz C, Chabrier G, Pugeat M, Young J, Hardelin JP, Prevot V, Dodé C. PLoS Genet. 2012 Aug;8(8):e1002896. doi: 10.1371/journal.pgen.1002896.

  4. Alteration in neonatal nutrition causes perturbations in hypothalamic neural circuits controlling reproductive function. Caron E, Ciofi P, Prevot V, Bouret SG. J Neurosci. 2012 Aug 15;32(33):11486-94. doi: 10.1523/JNEUROSCI.6074-11.2012.

  5. Embryonic birthdate of hypothalamic leptin-activated neurons in mice. Ishii Y, Bouret SG. Endocrinology. 2012 Aug;153(8):3657-67. doi: 10.1210/en.2012-1328.

  6. Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation. Coupé B, Ishii Y, Dietrich MO, Komatsu M, Horvath TL, Bouret SG. Cell Metab. 2012 Feb 8;15(2):247-55. doi: 10.1016/j.cmet.2011.12.016.

  7. Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits. Bouret SG, Bates SH, Chen S, Myers MG Jr, Simerly RB. J Neurosci. 2012 Jan 25;32(4):1244-52. doi: 10.1523/JNEUROSCI.2277-11.2012.

  8. Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation. Hanchate NK, Parkash J, Bellefontaine N, Mazur D, Colledge WH, d’Anglemont de Tassigny X, Prevot V. J Neurosci. 2012 Jan 18;32(3):932-45. doi: 10.1523/JNEUROSCI.4765-11.2012.

  9. MRI atlas of the human hypothalamus. Baroncini M, Jissendi P, Balland E, Besson P, Pruvo JP, Francke JP, Dewailly D, Blond S, Prevot V. Neuroimage. 2012 Jan 2;59(1):168-80. doi: 10.1016/j.neuroimage.2011.07.013.

Book Chapters

  1. Neuroendocrine control of reproduction Clarke IJ, Campbell R, Smith JT, Prevot V, Wray S In: Handbook of Neuroendocrinology (Fink G, Pfaff DW, Levine JE, Eds), Academic Press, San Diego, CA, Chapter 9, pp 197-235, 2012

  2. Isolation and culture of human astrocytes Sharif A, Prevot V Methods Mol Biol 814:137-151, 2012

2011

Original Research Articles

  1. Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility. Messina A, Ferraris N, Wray S, Cagnoni G, Donohue DE, Casoni F, Kramer PR, Derijck AA, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P. Hum Mol Genet. 2011 Dec 15;20(24):4759-74. doi: 10.1093/hmg/ddr403.

  2. Prostaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation. Clasadonte J, Poulain P, Hanchate NK, Corfas G, Ojeda SR, Prevot V. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16104-9. doi: 10.1073/pnas.1107533108.

  3. Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring. Steculorum SM, Bouret SG. Endocrinology. 2011 Nov;152(11):4171-9. doi: 10.1210/en.2011-1279.

Review Articles

  1. Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction Bellefontaine N, Hanchate NK, Parkash J, Campagne C, de Seranno S, Clasadonte J, d’Anglemont de Tassigny X, Prevot V Neuroendocrinology 93:74-89, 2011

  2. Gliotransmission by prostaglandin E2: a prerequisite for GnRH neuronal function Clasadonte J, Sharif A, Baroncini M, Prevot V Front Endocrinol 2:1-12, 2011

  3. GnRH neurons directly listen to the peripher  Prevot V Endocrinology 152: 3589-3591, 2011

2010

Original Research Articles

  1. Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric oxide production during the ovarian cycle. Parkash J, d’Anglemont de Tassigny X, Bellefontaine N, Campagne C, Mazure D, Buée-Scherrer V, Prevot V. Endocrinology. 2010 Jun;151(6):2723-35. doi: 10.1210/en.2010-0007.

  2. Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence. De Seranno S, d’Anglemont de Tassigny X, Estrella C, Loyens A, Kasparov S, Leroy D, Ojeda SR, Beauvillain JC, Prevot V. Endocrinology. 2010 Apr;151(4):1760-72. doi: 10.1210/en.2009-0870.

  3. Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain. Mullier A, Bouret SG, Prevot V, Dehouck B. J Comp Neurol. 2010 Apr 1;518(7):943-62. doi: 10.1002/cne.22273.

  4. Distribution of leptin-sensitive cells in the postnatal and adult mouse brain. Caron E, Sachot C, Prevot V, Bouret SG J Comp Neurol. 2010 Feb 15;518(4):459-76. doi: 10.1002/cne.22219.

  5. Sex steroid hormones-related structural plasticity in the human hypothalamus. Baroncini M, Jissendi P, Catteau-Jonard S, Dewailly D, Pruvo JP, Francke JP, Prevot V. Neuroimage. 2010 Apr 1;50(2):428-33. doi: 10.1016/j.neuroimage.2009.11.074.

Review Articles

  1. Plasticity of neuroendocrine systems Prevot V Eur J Neurosci 32:1987-1988, 2010

  2. GnRH nerve terminals, tanycytes and neurohaemal junction remodeling in the adult median eminence: functional consequences for reproduction and dynamic role of vascular endothelial cells Prevot V, Bellefontaine N, Baroncini M, Sharif A, Hanchate NK, Parkash J, Campagne C, de Seranno S J Neuroendocrinol 22:639-649, 2010

  3. Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions Prevot V, Hanchate NK, Bellefontaine N, Sharif A, Parkash J, Estrella C, Allet C, de Seranno S, Campagne C, de Tassigny X, Baroncini M Front Neuroendocrinol 31:241-258, 2010

  4. ErbB receptor signaling in astrocytes: a mediator of neuron-glia communication in the mature central nervous system Sharif A, Prevot V Neurochem Int 57:344-358, 2010